Immunohistochemistry Catalog
DOG1
Clone: DOG1.1
Cat#: 10119
DOG1 is expressed ubiquitously in gastrointestinal stromal tumors (GIST) irrespective of kit or PDGFR alpha mutation status. Reactivity for DOG1 may aid in the diagnosis of GISTs, including PDGFRA mutants that fail to express KIT antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the KIT tyrosine kinase.
Located in: Mouse Monoclonal Anti-