Immunohistochemistry Catalog
Entries with Names starting with 'H'
HISTOLS® c-erbB-2/HER2/neu (Two in One)
Clone: SP3+A24-V
Cat#: 10101
This mixture is a combination of a rabbit monoclonal (SP3) and a rabbit clonal (A24-V) antibody. It recognizes the c-erbB-2 protein on both its extracellular and intracellular domain. c-erbB-2/HER2/neu is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal grovvth factor receptor. c-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarcinomas, as well as transitional cell carcinomas.
Fixed-embedded human breast cancer
HISTOLS® p504S/p63
Clone: 13H4+4A4
Cat#: 10050
This mixture of rabbit monoclonal (13H4) and mouse monoclonal (4A4) antibodies is helpful in distinguishing malignant from benign cells. Combined detection of p504S and p63 is useful for the diagnosis of prostate cancers. P504S is expressed in prostatic adenocarcinomas but not in benign glands. p63 is detectable in benign basal cells of the prostate and in other epithelial tissues. p504S is positive in cytoplasm of malignant and premalignant prostate glands, anti-p63 antibody is positive in benign glandular basal layer nuclei.
Fixed-embedded human prostate
HISTOLS®- DAB
Cat#: 30014
DAB (3,3'-Diaminobenzidine) leads to the formation of a dark-brown precipitate at the location of the target antigen. The precipitate is insoluble in aqueous and organic solvents allowing the use of commonly known mounting media. This chromogen/substrate system is especially useful when a high contrast between the chromogen and counter stain is desired. Compared to standard DAB staining kits the HISTOLS®-DAB Chromogen/Substrate System gives a darker brown color and a higher sensitivity.
HISTOLS®- Resistant AEC
Cat#: 30015
HISTOLS ® Resistant AEC Chromogen/Substrate System was developed for immunohistochemical staining procedures using horseradish peroxidase (HRP) labeled secondary antibody. AEC (3-amino-9-ethylcarbazol) leads to the formation of reddish-brown precipitate at the location of the target antigen. The precipitate is insoluble in aqueous and organic solvents, which allows the use of commonly known mounting media.
HISTOLS®- Resistant AP Red
Cat#: 30019
HISTOLS®-AP Red Chromogen/Substrate System was developed for immunohistochemical staining procedures and will produce red colored deposit upon reaction with alkaline phosphatase at the site of the target antigen. The precipitate is insoluble in aqueous and organic solvents, which allows the use of commonly known mounting media.
HISTOLS®-QuANT
Cat#: 40017
For characterization of the cells participating in immunoresponse of a malignant tumor, we recommend staining for CD8 (cytotoxic T cells) and CD205 (APC). With help of the Tissue MicroArray Builder Kit we can create tissue cores with standard surface areas, which make quantitative evaluation easy.
Human Chorionic Gonadotropin β (hCG β)
Clone: 5H4E2
Cat#: 10022
5H4E2 labels the cytoplasm of HCG B producing cells in placenta, mola hydatidosa, choriocarcinoma, embryonal carcinoma seminoma and some undifferenciated lung cancers. It does not react with cells of normal endometrial, testicular tissues and lung.
Fixed-embedded human seminoma