Immunohistochemistry Catalog
Mouse Monoclonal Anti-
Actin (muscle specific)
Clone: HHF35
Cat#: 10123
HHF3 reacts with actin from tissue extracts of uterus, ileum, aorta, diaphragm, heart, and smooth muscle cells. It recognizes the alpha actin from skeletal, cardiac, and smooth muscle and the gamma actin from smooth muscle sources.
Actin (smooth muscle)
Clone: 1A4
Cat#: 10102
1A4 antibody does not stain cardiac or skeletal muscle; however, it stains myofibroblasts and myoepithelial cells.
Fixed-embedded human tissue
Aquaporin1 (AQP1)
Clone: 1/22
Cat#: 10029
1/22 reacts on the intracellular C-terminal AQPl epitope of aquaporins which are members of the Major Intrinsic Protein family.
Fixed-embedded rat brain
Aquaporin4 (AQP4)
Clone: 4/18
Cat#: 10030
4/18 reacts on the intracellular C-terminal AQP4 epitope of aquaporins, which are members of the Major Intrinsic Protein family.
Fixed-embedded rat brain
CD31
Clone: JC-70
Cat#: 10107
The antibody strongly labels endothelial cells and is valuable for the demonstration of capillaries and neoplasms arising from endothelial cells.
Fixed-embedded human tissue
CD34
Clone: QBEND/10
Cat#: 10085
CD34 is a 110 kDa molecular weight glycoprotein present on the surface of hemopoietic cells (i. e. myeloid and lymphoid progenitors) and vascular endothelial cells.
Fixed-embedded human placenta
CD45RB
Clone: PD/26
Cat#: 10124
This CD45 isoform is expressed by thymocytes, peripheral B cells and a subpopulation of T cells at high and by dendritic cells and macrophages at low density.
CD45RO
Clone: uCHL-1
Cat#: 10109
Anti-CD45RO (T-Cell, Pan) antibody reacts with thymocytes and activated T-cells, but only on a subpopulation of resting T-cells. This antibody shows no reactivity with B-cells making it a good marker for T-cell tumors. Granulocytes and monocytes are also labelled with this antibody.
Fixed-embedded human lymphoid
CD57
Clone: NK-1
Cat#: 10111
CD57 is found on natural killer cells and CD8+ lymphocytes. These cells play a role in the rejection of grafts in acute graft versus host disease. The CD57 molecule is not expressed on erythrocytes or platelets.
CD68
Clone: KP1
Cat#: 10112
CD68 is expressed by monocytes, macrophages and myeloid cells. Immunodetectio n of this antigen is useful for detection of reactive macrophages in a wide variety of norma! and pathological conditions and for immunophenotyping of myeloid and histiocytic cells and their neoplastic equivalents.
CD79a
Clone: JCB117
Cat#: 10114
These antibodies recognize an extracellular epitope expressed on the CD79a molecule, and detects the full spectrum of B-cells. CD79a has been found to be co-expressed with CD3 in 10% of cases of T- lymphoblastic leukemia/ lymphoma . Useful in the differential diagnosis of Hodgkin's disease.
CEA
Clone: COL1
Cat#: 10116
ln breast carcinomas, CEA (carcinoembryonic antigen, CD66e) staining correlated well with clinical outcome, independent of histologic type of tumors (with or without metastases) . Pancreatic carcinomas, testicular tumor, gall bladder neoplasms and granular cell myoblastomas sta in positive, whereas malignant tumors of brain, prostate, skin, lymphoreticular tissues, hepatocellular carcinomas, esophageal squamous cell carcinomas, and mesothelioma fai! to stain for CEA.
Fixed-embedded human colon
Chromogranin A
Clone: LK2H10
Cat#: 10117
Chromogranin A is present in a wide variety of endocrine tissues including the pituitary, pancreas, hypothalamus, thymus, thyroid, intestine, and parathyroid. Co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Fixed -embedded human pancreas
Cytokeratin (HMW)
Clone: 34βE12
Cat#: 10127
This antibody recognizes cytokeratins 1,5,10, and 14 that are found in complex epithelia. The 34βE12 labels myopeithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from hyperplasia of the prostate. This antibody is also been useful in separating benign from malignant intraductal breast proliferations.
Fixed-embedded human prostate