Lectures
Please pay attention that the below lecture slides alone are not suitable for learning the subject Basic Immunology because they are incomplete without the live explanations and additions given on the lectures by our teachers. For the complete understanding of our topics we expect that students take part on the lectures and make their own notes as well as the use of the Textbook: Abul K. Abbas et al.: Molecular and Cellular Immunology 10th Edition 2021.
1-2. Introduction. Components and structure of the immune network.
3. Innate immunity. Pattern recognition.
4. Innate immunity. Inflammatory reaction.
5.-6. Structure, classes and functions of immunoglobulins and T cell receptors. Recognition and presentation of antigens by MHC.
7.-8. Communication between the cellular components of the immune system.
9. Organization and rearrangement of the antigen receptor genes.
10. Primary B cell differentiation
11. T-cell development in the thymus. Stages of maturation and the role of environmental factors.
12. Initial phase of the immune response. T cell activation, CD3 complex and signaling. Costimulation. Peripheral T cell differentiation.
13.-14. Humoral immune responses: extrafollicular reaction and germinal center reactions - affinity maturation and isotype switch.
15. Effector functions of immunoglobulins.
16. The complement system.
17. Effector mechanisms of the cell-mediated immune responses.
18. Maintenance of the immunological memory and its role in immune response regulation. Comparison of the primary- and secondary immune response.
19-20. Suppression of the immune response. Systemic and local immunity (SALT, MALT).
21-22. Hypersensitive reactions.
23-24. Tolerance and autoimmunity.
25.-26. Tumor immunology. Immunological aspects of transplantation.
27. Primary immunodeficiencies.
28. Acquired immunodeficiencies. HIV-AIDS.